Key result
Perfusion index strongly predicts post-induction hypotension during general anesthesia with an AUC of 0.89.
Why the study?
Post-induction hypotension is a common and potentially serious complication of general anesthesia, prompting evaluation of the predictive efficacy of the perfusion index.
Does the perfusion index measured before anesthesia induction predict post-induction hypotension in adult patients undergoing general anesthesia?
Meta-Analysis (n=678)
Does the perfusion index measured before anesthesia induction predict post-induction hypotension in adult patients undergoing general anesthesia?
The perfusion index measured before anesthesia induction demonstrates high predictive efficacy for post-induction hypotension, serving as a valuable risk stratification tool.
This is the authors' abstract. We don't add key points for this paper.
Post-induction hypotension (PIH) is a common and potentially serious complication of general anesthesia. This meta-analysis (Prospero registration number: CRD42024566321) aimed to evaluate the predictive efficacy of the perfusion index (PI) for PIH in patients undergoing general anesthesia. A comprehensive literature search was performed using multiple electronic databases (Google Scholar, EMBASE, Cochrane Library, and MEDLINE). Studies involving adult patients undergoing general anesthesia, with the PI measured before anesthesia induction and reporting PIH incidence, were included. The primary outcome was the diagnostic accuracy of the PI in predicting the probability of PIH. The secondary outcome was the pooled PIH incidence. Eight studies with 678 patients were included. The pooled incidence of PIH was 44.8% (95% confidence interval [CI]: 29.9%-60.8%). The combined sensitivity and specificity of the PI for predicting PIH were 0.84 (95% CI: 0.65-0.94) and 0.82 (95% CI: 0.70-0.90), respectively. The summary receiver operating characteristic (sROC) analysis revealed an area under curve of 0.89 (95% CI: 0.86-0.92). The Deek's funnel plot asymmetry test indicated no significant publication bias. The PI demonstrates high predictive efficacy for PIH in patients undergoing general anesthesia, indicating that it can be a valuable tool for identifying those at risk of PIH.
Answers are grounded in this paper and cite their sources.
Supports pre-induction perfusion index use for hypotension risk stratification in anesthesia; confirms high predictive accuracy via meta-analysis.
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Hung et al. (2024) conducted a meta-analysis in Post-induction hypotension in general anesthesia (n=678). Perfusion index (PI) was evaluated on Diagnostic accuracy of the PI in predicting the probability of post-induction hypotension (AUC 0.89, 95% CI 0.86-0.92). The perfusion index demonstrated high predictive efficacy for post-induction hypotension in patients undergoing general anesthesia, with an area under the curve of 0.89.
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