What is the clinical evidence from this study?

Study design: Case Report. Population: Ampulla (Takotsubo) Cardiomyopathy and Secondary Adrenal Insufficiency (n=1). Intervention: Hydrocortisone. Primary outcome: Recovery of left ventricular wall motion.

What does this research mean for the field?

Hydrocortisone treatment in a patient with Takotsubo cardiomyopathy triggered by severe hypoglycemia and ACTH deficiency leads to recovery of cardiac wall motion. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 2007Endocrine JournalOpen Access

Ampulla (Takotsubo) Cardiomyopathy Caused by Secondary Adrenal Insufficiency in ACTH Isolated Deficiency

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Population

1 53-year-old woman with unconsciousness due to hypoglycemia, diagnosed with secondary adrenal insufficiency…

Design

Case_report

Follow-up

2 weeks

Key result

Hydrocortisone treatment in a 53-year-old woman with Takotsubo cardiomyopathy triggered by severe hypoglycemia (34 mg/dL) and ACTH deficiency led to recovery of cardiac wall motion at 2 weeks.

Authors

SSSatoru Sakihara KKKazunori Kageyama TNTakeshi Nigawara

Discussion

Member takes

Overview

May support evaluating ACTH deficiency in Takotsubo cardiomyopathy; leaves open whether glucocorticoid replacement improves outcomes.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

1 53-year-old woman with unconsciousness due to hypoglycemia, diagnosed with secondary adrenal insufficiency in ACTH isolated deficiency and takotsubo cardiomyopathy.

Intervention

Hydrocortisone 200 mg/day intravenously for one week, then 15 mg/day orally for a further week

Outcome

Recovery of left ventricular wall motion and ejection fractionsurrogate

Secondary adrenal insufficiency in ACTH isolated deficiency can trigger reversible takotsubo cardiomyopathy, which improves with appropriate glucocorticoid replacement.

Cite This Study

Sakihara et al. (2007) conducted a case report in Ampulla (Takotsubo) Cardiomyopathy and Secondary Adrenal Insufficiency (n=1). Hydrocortisone was evaluated on Recovery of left ventricular wall motion. Hydrocortisone treatment in a 53-year-old woman with Takotsubo cardiomyopathy triggered by severe hypoglycemia (34 mg/dL) and ACTH deficiency led to recovery of cardiac wall motion at 2 weeks.

synapsesocial.com/papers/6a14639ef88db7183c5a0250 https://doi.org/10.1507/endocrj.k07-012

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January 1, 2007Endocrine JournalOpen Access

Ampulla (Takotsubo) Cardiomyopathy Caused by Secondary Adrenal Insufficiency in ACTH Isolated Deficiency

View Full Paper

Ask AI

Bookmark

Population

1 53-year-old woman with unconsciousness due to hypoglycemia, diagnosed with secondary adrenal insufficiency…

Design

Case_report

Follow-up

2 weeks

Key result

Hydrocortisone treatment in a 53-year-old woman with Takotsubo cardiomyopathy triggered by severe hypoglycemia (34 mg/dL) and ACTH deficiency led to recovery of cardiac wall motion at 2 weeks.

Authors

SSSatoru Sakihara KKKazunori Kageyama TNTakeshi Nigawara

Discussion

Member takes

Overview

May support evaluating ACTH deficiency in Takotsubo cardiomyopathy; leaves open whether glucocorticoid replacement improves outcomes.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

1 53-year-old woman with unconsciousness due to hypoglycemia, diagnosed with secondary adrenal insufficiency in ACTH isolated deficiency and takotsubo cardiomyopathy.

Intervention

Hydrocortisone 200 mg/day intravenously for one week, then 15 mg/day orally for a further week

Outcome

Recovery of left ventricular wall motion and ejection fractionsurrogate

Secondary adrenal insufficiency in ACTH isolated deficiency can trigger reversible takotsubo cardiomyopathy, which improves with appropriate glucocorticoid replacement.

Cite This Study

synapsesocial.com/papers/6a14639ef88db7183c5a0250 https://doi.org/10.1507/endocrj.k07-012

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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