What does this research mean for the field?

The overestimation of infarct size by quantitative two-dimensional echocardiography is caused by a combination of myocardial tethering and analytic artifacts from standard center of mass algorithms due to systolic axis shifts. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

June 1, 1986CirculationOpen Access

Overestimation of infarct size by quantitative two-dimensional echocardiography: the role of tethering and of analytic procedures.

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Population

12 animals undergoing short-axis view echocardiography for infarct size assessment

Comparison

Quantitative two-dimensional echocardiographic… vs Contrast two-dimensional echocardiography

Design

Preclinical

Authors

TFThomas ForceCardio-Oncology AKAndrew J. KemperNorth Shore Medical Center LPLorri A. PerkinsFox Chase Cancer Center

Discussion

Member takes

Implication

Center-of-mass analysis may overestimate infarct size; extends mechanistic insights but requires human validation before clinical use.

Structured PICO

Population

12 animals undergoing short-axis view echocardiography for infarct size assessment

Intervention

Quantitative two-dimensional echocardiographic analysis of systolic thickening using center of mass algorithms

Comparator

Contrast two-dimensional echocardiography (echo contrast defect)

Outcome

Correlation between extent of dysfunction by center of mass analysis and echo contrast defect sizesurrogate

Overestimation of infarct size by 2D echocardiography center of mass analysis is caused by both myocardial tethering and analytic artifacts from systolic shift.

Cite This Study

Force et al. (1986) studied this question.

synapsesocial.com/papers/6a14872e9bbe6abf638ee83b https://doi.org/10.1161/01.cir.73.6.1360

Topics

Echocardiography

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Overestimation of infarct size by quantitative two-dimensional echocardiography: the role of tethering and of analytic procedures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Overestimation of infarct size by quantitative two-dimensional echocardiography: the role of tethering and of analytic procedures.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

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