Key result
Rheumatoid arthritis was associated with significantly reduced small and large artery elasticity and increased systemic vascular resistance compared with matched controls.
Why the study?
Is arterial elasticity reduced and systemic vascular resistance increased in patients with rheumatoid arthritis compared to matched controls?
Population
106 individuals, comprising 53 patients with rheumatoid arthritis and 53 controls matched 1:1 for age, sex…
Comparison
Rheumatoid arthritis (disease exposure) vs Controls matched 1:1 for age, sex, and CAD status
Design
Case-control
Authors
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Alerts clinicians to subclinical vascular impairment in RA; extends CV risk observations but leaves causal and interventional questions open.
Case-Control (n=106)
Is arterial elasticity reduced and systemic vascular resistance increased in patients with rheumatoid arthritis compared to matched controls?
Rheumatoid arthritis is associated with abnormal vascular function, including reduced arterial elasticity and increased systemic vascular resistance, which correlates with systemic inflammation.
Wong et al. (2003) conducted a case-control in Rheumatoid arthritis (n=106). Rheumatoid arthritis vs. Matched controls was evaluated on Small artery elasticity, large artery elasticity, and systemic vascular resistance. Rheumatoid arthritis was associated with significantly reduced small and large artery elasticity and increased systemic vascular resistance compared with matched controls.
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