Key result
A short period of apnoea in healthy men increased maximal coronary blood flow velocity in the left anterior descending artery by 62% from 0.26 to 0.42 m/s.
Why the study?
Does a short period of apnoea increase coronary flow velocity in healthy men?
Observational (n=10)
Does a short period of apnoea increase coronary flow velocity in healthy men?
Answers are grounded in this paper and cite their sources.
A short period of apnoea significantly increases coronary flow velocity, which is important to consider to avoid misinterpretation during imaging studies like MRI or Doppler that utilize breath holding.
Coronary artery flow velocity during a short period of apnoea was investigated by transthoracic Doppler recording in 10 healthy men, aged 24-52. During breath holding for 29 +/- 6 s the oxygen saturation in the finger, measured by pulse oxymetry, decreased from 97.5 +/- 0.8 to 90.0 +/- 3.2% (P < 0.001). The maximal coronary blood flow velocity in the left anterior descending artery increased by 62% from 0.26 +/- 0.09 to 0.42 +/- 0.10 m s(-1) and the mean diastolic flow velocity by 47% from 0.19 +/- 0.04 to 0.28 +/- 0.08 m s(-1) (P < 0.001). In most subjects the increase of velocity started already after a few seconds of apnoea. Besides theoretical implications the results show that it is very important to be aware of the higher velocity during apnoea in order to avoid misinterpretation when using breath holding during magnetic resonance imaging or Doppler recording of coronary flow.
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Gan et al. (2005) conducted an observational in Healthy (n=10). Short period of apnoea (breath holding) vs. Baseline was evaluated on Maximal coronary blood flow velocity in the left anterior descending artery (62% increase, p=<0.001). A short period of apnoea in healthy men increased maximal coronary blood flow velocity in the left anterior descending artery by 62% from 0.26 to 0.42 m/s.
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