Key result
Symptoms, left ventricular function, and response to exercise are the most important prognostic indicators for determining the timing of aortic valve replacement in chronic severe aortic regurgitation.
Why the study?
What are the most important prognostic indicators for determining the timing of aortic valve replacement in chronic severe aortic regurgitation?
What are the most important prognostic indicators for determining the timing of aortic valve replacement in chronic severe aortic regurgitation?
Symptoms, left ventricular function, and response to exercise are key prognostic indicators for timing aortic valve replacement in chronic severe aortic regurgitation.
Highlights symptoms and LV function for AVR timing decisions in severe AR; leaves open prospective validation of exercise thresholds.
When deciding on therapy for aortic regurgitation (AR), it is imperative to distinguish between acute and chronic AR. Symptoms and echocardiographic findings are essential in distinguishing acute from chronic AR and in assessing the severity. Vasodilators have been shown to be helpful in treating patients with chronic severe AR. The timing of aortic valve replacement in chronic severe AR remains controversial. Symptoms, left ventricular function, and response to exercise have been shown to be the most important prognostic indicators.
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Katz et al. (2000) conducted a review in Chronic Aortic Regurgitation. Aortic valve replacement was evaluated. Symptoms, left ventricular function, and response to exercise are the most important prognostic indicators for determining the timing of aortic valve replacement in chronic severe aortic regurgitation.
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