Key result
Older age (HR 1.214), mechanical ventilation (HR 10.106), and raised CK-MB (HR 1.005) significantly predicted in-hospital death in elderly patients (>75 years) diagnosed with acute coronary syndrome.
Why the study?
Predictors of death in elderly patients diagnosed with acute coronary syndrome needed to be analyzed.
Does percutaneous coronary intervention improve in-hospital survival compared to medical management in elderly patients (>75 years) with acute coronary syndrome?
Observational (n=179)
No
Does percutaneous coronary intervention improve in-hospital survival compared to medical management in elderly patients (>75 years) with acute coronary syndrome?
Effect estimate: HR 1.214 (95% CI 1.122-1.384)
p-value: p=<0.0001
In elderly patients (>75 years) with ACS, in-hospital mortality is high (11.7%) and strongly predicted by advanced age, mechanical ventilation, and elevated CK-MB, with no apparent survival benefit observed from PCI in this retrospective cohort.
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These predictors may aid risk stratification in elderly ACS; leaves open whether PCI improves survival versus medical management.
Ahmed et al. (2019) conducted an observational in Acute coronary syndrome (ACS) (n=179). Age (as a predictor) was evaluated on In-hospital death (HR 1.214, 95% CI 1.122-1.384, p=<0.0001). Older age (HR 1.214), mechanical ventilation (HR 10.106), and raised CK-MB (HR 1.005) significantly predicted in-hospital death in elderly patients (>75 years) diagnosed with acute coronary syndrome.
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