Measuring myocardial extracellular volume of the right ventricle in patients with congenital heart disease

Figures

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  Figure 1. Grades of image quality. Native (panel a) and post-contrast T1 maps (panels b + c) with image quality rated as a: excellent (score grade 1) in a 39-year-old patient with repaired tetralogy of Fallot; b: sufficient (score grade 2) in a 37-year-old patient with d-transposition of the great arteries post atrial redirection with the Senning procedure; c: poor (score grade 3) in a 23-year-old patient with univentricular heart post Fontan palliation. Definitions of grades 1–3 are given in Table 1. Images were created using OsiriX Lite (v.12.0.0, https://www.osirix-viewer.com/).

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  Figure 2. Image quality and wall thickness for T1 mapping of the right ventricle. Representative native T1 map of a 36-year-old patient with pulmonary stenosis demonstrating excellent image quality (score grade 1; panel a) and right ventricular wall thickness of 1 pixel per region of interest (score grade 2; panels b + c). Images were created using OsiriX Lite (v.8.5, https://www.osirix-viewer.com/).

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  Figure 3. Example of T1 map in congenital heart disease. Representative native T1 map of a 47-year-old patient with palliated pulmonary atresia and ventricular septal defect showing region of interest (green) and corresponding line of interest (blue) in the right ventricle in short axis orientation. Images were created using OsiriX Lite (v.8.5, https://www.osirix-viewer.com/).

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  Figure 4. Extracellular volume—region of interest versus line of interest. Correlation (a) and Bland–Altman analysis (b) of right ventricular myocardial extracellular volume (RV ECV) from regions of interest (ROIs) and corresponding lines of interest (LOIs) in short axis orientation across healthy controls and patients with congenital heart disease.