Key result
Galangin normalizes cardiorenal dysfunction and hypertrophy in rats via Nox-4 and Nrf-2/HO-1 protein modulation.
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Hypothesis-generating for galangin in cardiorenal injury; human trials needed before any clinical consideration.
R/Nox-4 and Nrf-2/HO-1 protein in renal tissue in hypertensive rats.
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Chaihongsa et al. (2022) studied this question. Galangin treatment normalized cardiorenal dysfunction and hypertrophy in rats with renal artery occlusion, associated with R/Nox-4 and Nrf-2/HO-1 protein modulation.
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