Key result
Low-dose non-contrast MDCT provided superior visualization of bileaflet mechanical aortic valves compared to fluoroscopy and strongly correlated with valve angles.
Why the study?
Does a low-mA, non-contrast MDCT protocol accurately evaluate bileaflet mechanical aortic valve function compared to fluoroscopy and echocardiography in patients with mechanical aortic valves?
Observational (n=40)
Does a low-mA, non-contrast MDCT protocol accurately evaluate bileaflet mechanical aortic valve function compared to fluoroscopy and echocardiography in patients with mechanical aortic valves?
Answers are grounded in this paper and cite their sources.
Low-dose, non-contrast MDCT provides superior visualization and accurate functional assessment of mechanical aortic valves compared to traditional fluoroscopy and echocardiography.
Background Prosthetic bileaflet mechanical valve function has been traditionally evaluated using echocardiography and fluoroscopy. Multidetector computed tomography (MDCT) is a novel technique for cardiac evaluation. Purpose To evaluate bileaflet mechanical aortic valves using a low-milliampere (mA), non-contrast MDCT protocol with a limited scan range. Material and Methods Forty patients with a bileaflet mechanical aortic valve were evaluated using a non-contrast, low-mA, ECG-gated 64 MDCT protocol with a limited scan range. MDCT findings of opening and closing valve angles were correlated to fluoroscopy and echocardiography. Also, the valve visibility was evaluated on MDCT and fluoroscopy according to a 3-point grading scale. Results The visualization score with the MDCT was significantly superior to the fluoroscopy (3 vs. 2.7). A strong correlation was noted between the opening (r = 0.82) and closing (r = 0.96) valve angles with MDCT and fluoroscopy without a statistically significant difference ( P = 0.31 and 0.16, respectively). The mean effective radiation dose of the suggested protocol was 4 ± 0.5 mSv. Five valves were evaluated using transesophageal echocardiography because the valves were difficult to evaluate with transthoracic echocardiography, and all of these valves were evaluated optimally with MDCT. A high-pressure gradient was noted in nine valves, and the MDCT showed that seven of these valves inadequately opened, and two valves opened well, which resulted in patient valve mismatch. Incomplete valve closure was noted in five valves, and the echocardiography showed significant transvalvular regurgitation in all five valves. Conclusion MDCT can provide a precise measurement of valve function and can potentially evaluate high-pressure gradients and transvalvular regurgitation.
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Bazeed et al. (2012) conducted an observational in Bileaflet mechanical aortic valve (n=40). Non-contrast, low-mA, ECG-gated 64 MDCT vs. Fluoroscopy and echocardiography was evaluated on Visualization score. Low-dose non-contrast MDCT provided superior visualization of bileaflet mechanical aortic valves compared to fluoroscopy and strongly correlated with valve angles.
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