Why the study?
Does acute beta-blockade or vasodilatation improve arterial hemodynamic indexes in patients with Marfan's syndrome?
Does acute beta-blockade or vasodilatation improve arterial hemodynamic indexes in patients with Marfan's syndrome?
Acute beta-blockade increases wave reflection and reduces arterial compliance in Marfan's syndrome, suggesting it may not be beneficial for reducing hemodynamic loading on a dilated aortic root.
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Questions beta-blocker hemodynamics in Marfan aortopathy; challenges consensus and leaves open randomized outcome trials.
Yin et al. (1989) studied this question.
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