Key result
Scanning electron microscopy of whole blood and platelet-rich plasma demonstrated that physical clot formation, including fibrin cross-linking, correlates directly with thrombelastography tracings.
Population
Blood samples including whole blood, abciximab-treated whole blood, platelet-rich plasma, and…
Design
Preclinical
Authors
Loading...
Confirms TEG tracings reflect physical clot structure in animal blood; leaves open human validation before clinical use.
Scanning electron microscopy confirms that physical clot formation and structural changes correlate directly with thrombelastography (TEG) variables.
Kawasaki et al. (2004) studied this question. Abciximab vs. Untreated whole blood and platelet-rich plasma was evaluated on Clot morphology and structural changes at time points corresponding to thrombelastography variables. Scanning electron microscopy of whole blood and platelet-rich plasma demonstrated that physical clot formation, including fibrin cross-linking, correlates directly with thrombelastography tracings.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: