PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
September 10, 2018Brain ConnectivityOpen Access

Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does problem drinking and alcohol expectancy correlate with thalamic resting-state functional connectivity in nondependent adult drinkers?

Population

107 nondependent adult drinkers (57 women)

Design

Cross-sectional

Key result

In nondependent adult drinkers, problem drinking was associated with increased thalamic connectivities, and alcohol expectancy completely mediated the correlation between thalamic caudate connectivity and problem drinking.

Authors

SZSimon ZhornitskyJIJaime S. IdeWWWuyi Wang

Discussion

Loading...

Member takes

Overview

Thalamic connectivity may link to problem drinking via expectancy in nondependent adults; leaves open causality and clinical relevance.

Study Design

Type

Cross-Sectional (n=107)

Multicenter

No

Structured PICO

Does problem drinking and alcohol expectancy correlate with thalamic resting-state functional connectivity in nondependent adult drinkers?

P
Population
107 nondependent adult drinkers (57 women)
O
Outcome
Correlation of resting-state functional connectivity (rsFC) of thalamic subregions with Alcohol Use Disorders Identification Test (AUDIT) and positive alcohol expectancy (AE) scoresurrogate

Increased thalamic caudate connectivity may contribute to problem drinking via enhanced alcohol expectancy in nondependent drinkers.

Limitations

  • Lack of behavioral tests to link findings to cognitive or affective dysfunction
  • Higher AUDIT score and monthly drinking frequency in men than in women
  • Menstrual cycles in female participants were not documented
  • Alcohol expectancy assessed by questionnaires may involve logistic and methodological issues

Cite This Study

Zhornitsky et al. (2018) conducted a cross-sectional in Problem drinking in nondependent drinkers (n=107). Problem drinking and alcohol expectancy was evaluated on Correlation of thalamic resting-state functional connectivity with AUDIT and alcohol expectancy scores. In nondependent adult drinkers, problem drinking was associated with increased thalamic connectivities, and alcohol expectancy completely mediated the correlation between thalamic caudate connectivity and problem drinking.

synapsesocial.com/papers/6a153083a2352da34782077ahttps://doi.org/10.1089/brain.2018.0633
View Full Paper
Ask AI
Bookmark
Share