Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.1992 · 695 citations
2. 2Absence of yolk sac hematopoiesis from mice with a targeted disruption of the scl gene.1995 · 591 citations
3. 3Homeodomain factor Nkx2-5 controls left/right asymmetric expression of bHLH gene eHand during murine heart development.1997 · 325 citations
4. 4Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects inBMP7 deficient embryos1997 · 446 citations