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January 1, 1964Physiological Reviews394 citations

Regulation of Coronary Blood Flow

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RBRobert M. Berne

Key Points

  • Investigate the mechanisms regulating coronary blood flow in response to platelet-activating factor (PAF) exposure.
  • Administered 2 nM platelet-activating factor (PAF) into a 1:5 diluted whole blood perfusion model for 30 seconds.
  • Perfusion of 2 nM PAF with diluted whole blood induced rapid alterations in coronary flow during the 30-second exposure window.
  • Vascular responses demonstrated acute regulatory dynamics in the coronary circulation.

Abstract

1 : 5 diluted whole blood has been passed for 30s after the addition of 2 nM PAF.See p. 174.

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Cite This Study

Robert M. Berne (1964) studied this question.

synapsesocial.com/papers/6a153780cb0379474a8204cdhttps://doi.org/10.1152/physrev.1964.44.1.1
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