Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients
Key result
ICD insertion linked to clinically relevant anxiety in ~23% of patients.
- 95% CI 18.26-26.91
- n=39,954
Why the study?
Implantable cardioverter defibrillators prevent sudden cardiac death, but anxiety, depression, and PTSD are underappreciated symptoms in this population.
Population
39 954 patients across 109 articles
Comparison
Comparisons with control groups, and within ICD patients by indication, sex, shock status, and over time
Design
Systematic review and random-effects meta-analysis
Authors
Discussion
Loading...
Member takes
Implication
Supports routine psychological screening in ICD patients; leaves open optimal intervention timing and efficacy.
Study Design
Type
Meta-Analysis (n=39,954)
Structured PICO
P
Population
39,954 patients with implantable cardioverter defibrillators (ICDs) pooled from 109 studies
I
Intervention
Implantable cardioverter defibrillator (ICD) insertion and subsequent shocks
C
Comparator
Control groups, or within ICD patients by indication (primary vs. secondary), sex, shock status, and over time
O
Outcome
Prevalence estimates of mood disorders (anxiety, depression, and post-traumatic stress disorder) and symptom severities pre- and post-ICD insertionspatient reported
Mood disorders including anxiety, depression, and PTSD are highly prevalent in patients with ICDs, particularly those who experience shocks, highlighting the need for routine psychological assessment and care.
Cite This Study
Ghezzi et al. (2023) conducted a meta-analysis in Implantable cardioverter defibrillator (ICD) patients (n=39,954). Implantable cardioverter defibrillators (ICDs) vs. Control groups or within ICD patients by indication, sex, and shock status was evaluated on Prevalence of clinically relevant anxiety following ICD insertion (95% CI 18.26-26.91). Implantable cardioverter defibrillator insertion was associated with clinically relevant anxiety in 22.58% (95% CI 18.26-26.91%) and depression in 15.42% of patients across all timepoints.