Key result
Transcatheter mitral valve repair was associated with a lower risk of 30-day readmission compared to surgical repair after propensity score adjustment (adjusted OR 0.70; 95% CI 0.51-0.95; p=0.02).
Why the study?
Data on 30-day readmissions after transcatheter mitral valve repair were limited.
Does transcatheter mitral valve repair reduce 30-day readmissions compared to surgical mitral valve repair in high-risk patients with mitral regurgitation?
Observational (n=8,912)
Yes
Does transcatheter mitral valve repair reduce 30-day readmissions compared to surgical mitral valve repair in high-risk patients with mitral regurgitation?
Effect estimate: adjusted OR 0.70 (95% CI 0.51-0.95)
Absolute Event Rate: 11.7% vs 10.7%
p-value: p=.02
In high-risk patients with mitral regurgitation, TMVR is associated with a significantly lower risk of 30-day readmission compared to SMVR after propensity adjustment.
TMVR associated with lower adjusted 30-day readmission in this cohort; hypothesis-generating and should not yet change practice.
OBJECTIVE: Determine the rates, reasons, predictors, and costs of 30-day readmissions following transcatheter mitral valve repair (TMVR) versus surgical mitral valve repair (SMVR) in the United States. BACKGROUND: Data on 30-day readmissions after TMVR are limited. METHODS: High-risk patients with mitral regurgitation (MR) undergoing TMVR or SMVR were identified from the 2014-2015 Nationwide Readmissions Databases. Multivariable stepwise regression models were used to identify independent predictors of 30-day readmission. Risk of 30-day readmission was compared between the two groups using univariate and propensity score adjusted regression models. RESULTS: Among 8,912 patients undergoing mitral valve repair during 2014-2015 (national estimate 17,809), we identified 7,510 (84.7%) that underwent SMVR and 1,402 (15.3%) that underwent TMVR. Thirty-day readmission rates after SMVR and TMVR were 10.7% and 11.7%, respectively (unadjusted OR 1.11, 95% CI 0.89-1.39, p = .35). After propensity score adjustment, TMVR was associated with a lower risk of 30-day readmissions compared with SMVR (adjusted OR 0.70, 95% CI 0.51-0.95, p = .02). Heart failure and arrhythmias were the leading cardiac reasons for readmission. Anemia and fluid and electrolyte disorder were independent predictors of 30-day readmission after TMVR. Demographics, comorbidities, and length of stay were independent predictors of 30-day readmission after SMVR. CONCLUSIONS: One in 10 patients are readmitted within 30 days following TMVR or SMVR. Approximately half of the readmissions are for cardiac reasons. The predictors of 30-day readmission are different among patients undergoing TMVR and SMVR, but can be easily screened for to identify patients at highest risk for readmission.
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Lima et al. (2019) conducted an observational in Mitral regurgitation (n=8,912). Transcatheter mitral valve repair (TMVR) vs. Surgical mitral valve repair (SMVR) was evaluated on 30-day readmission (adjusted OR 0.70, 95% CI 0.51-0.95, p=.02). Transcatheter mitral valve repair was associated with a lower risk of 30-day readmission compared to surgical repair after propensity score adjustment (adjusted OR 0.70; 95% CI 0.51-0.95; p=0.02).
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