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January 1, 1956Circulation Research200 citationsOpen Access

Time Relationship of Dynamic Events in the Cardiac Chambers, Pulmonary Artery and Aorta in Man

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EBEugene BraunwaldAFAlfred P. FishmanACAndré Cournand

Key Points

  • The aim is to investigate the time relationships between electric and mechanical events in the heart and large vessels.
  • Recorded pressure pulses in four cardiac chambers and large vessels during chest surgery.
  • Study included 13 individuals without cardiovascular disease.
  • Analyzed temporal sequences of cardiac events.
  • Confirmed classical observations of time relationships in cardiac events from earlier canine studies.
  • Detailed characteristics of similar phases in both sides of the heart were identified.

Abstract

Exposure of the heart in the course of chest surgery affords a means of faithfully recording pressure pulses in the four chambers of the heart and in the large vessels of human subjects. This study in 13 individuals without any clinical evidence of cardiovascular disease, is concerned with the time relationship between electric and mechanical events and with the temporal sequence and respective characteristics of similar phases of the cardiac cycle in both sides of the heart. The results obtained by permutation of simultaneous pressure recordings confirm the classical observations made in dogs.

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Cite This Study

Braunwald et al. (1956) studied this question.

synapsesocial.com/papers/6a153e70b2e0231f15822701https://doi.org/10.1161/01.res.4.1.100
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1An Analysis of Normal and Abnormal Left Atrial Pressure Pulse in Man1956 · 30 citations
  2. 2THE RELATIONSHIP BETWEEN ELECTRICAL AND MECHANICAL EVENTS IN THE CARDIAC CYCLE OF MAN1949 · 78 citations
  3. 3STUDY OF SIMULTANEOUS RIGHT AND LEFT ATRIAL PRESSURE PULSES UNDER NORMAL AND EXPERIMENTALLY ALTERED CONDITIONS1948 · 82 citations
  4. 4PHYSIOLOGY IN HEALTH AND DISEASE1945 · 76 citations
  5. 5Relation between electrical and mechanical events of the cardiac cycle in normal and abnormal clinical states.1947 · 13 citations