Key result
Combining the M1 constitutive law for the leaflet and the exponential law for chordae tendineae provides the most suitable simulation of mitral valve dynamics with fluid-structure interaction.
Why the study?
To evaluate the effects of different constitutive laws for mitral leaflets and chordae tendineae on mitral valve dynamics under fluid-structure interaction.
The choice of constitutive laws for mitral leaflets and chordae tendineae significantly impacts fluid-structure interaction simulation outcomes like regurgitation volume and orifice area.
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Optimizes mitral valve FSI modeling parameters; leaves open human validation and clinical translation.
Cai et al. (2019) studied Mitral valve dynamics. Constitutive laws for mitral valve simulation vs. Alternative constitutive laws was evaluated on Mitral valve dynamics (orifice area, regurgitation flow, stress/strain). Combining the M1 constitutive law for the leaflet and the exponential law for chordae tendineae provides the most suitable simulation of mitral valve dynamics with fluid-structure interaction.
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