Key result
A rise in systemic vascular resistance during cardiopulmonary bypass was associated with a reduced need for inotropic support, with 77% of these patients requiring no support.
Why the study?
Does the change in systemic vascular resistance during cardiopulmonary bypass predict the need for inotropic support in the immediate post-bypass period in adults?
Observational (n=56)
Does the change in systemic vascular resistance during cardiopulmonary bypass predict the need for inotropic support in the immediate post-bypass period in adults?
A failure to increase systemic vascular resistance during cardiopulmonary bypass is associated with a greater need for inotropic support in the immediate post-bypass period.
Answers are grounded in this paper and cite their sources.
May aid post-bypass risk stratification for inotropes; hypothesis-generating, needs prospective trials before practice change.
A clinical study was undertaken to measure changes in systemic vascular resistance during cardiopulmonary bypass in 56 adults. Forty-five patients snowed a rise in systemic vascular resistance and 77% required no inotropic support in the immediate post-bypass period. Eleven of the 33 patients undergoing valve replacement surgery showed only a small increase or an actual decrease in systemic vascular resistance and required inotropic support. These results were statistically significant. Factors affecting cardiac performance are discussed.
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Putnam et al. (1983) conducted an observational in Cardiopulmonary bypass (n=56). Systemic vascular resistance changes was evaluated on Requirement for inotropic support. A rise in systemic vascular resistance during cardiopulmonary bypass was associated with a reduced need for inotropic support, with 77% of these patients requiring no support.
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