Key result
Adult-specific order sets in a pediatric ICU fail to reduce hospital mortality for ACHD patients.
Why the study?
Patients with congenital heart disease increasingly survive to adulthood, but the optimal postoperative setting for their age- and condition-specific needs is not yet determined.
Does an adult-specific order set improve clinical outcomes in adults with congenital heart disease admitted to a pediatric cardiovascular ICU following cardiac surgery?
Cohort (n=219)
No
Does an adult-specific order set improve clinical outcomes in adults with congenital heart disease admitted to a pediatric cardiovascular ICU following cardiac surgery?
Effect estimate: RR 0.3
Absolute Event Rate: 2.3% vs 7.8%
p-value: p=.1
An adult-specific order set in a pediatric ICU did not improve overall outcomes for ACHD patients but may reduce mortality in those with higher anatomic complexity.
Does not support routine adoption of adult-specific order sets in pediatric ICUs for ACHD; leaves open possible mortality benefit in higher-complexity subgroups for prospective evaluation.
Background: Patients with congenital heart disease (CHD) are increasingly surviving to adulthood. Given their age- and condition-specific needs, the optimal postoperative setting for these patients is not yet determined. This study aims to evaluate the utility of an adult-specific order set in improving clinical outcomes for these patients in a pediatric cardiovascular intensive care unit (ICU). Methods: Adults with CHD (ACHD) admitted to the cardiovascular ICU following cardiac surgery at a pediatric tertiary care center were identified for a retrospective cohort study. Health care delivery metrics and clinical outcomes of participants who received the adult-specific order set were compared with control patients admitted prior to the intervention. Categorical outcomes were compared using the χ 2 test of independence or Fisher exact test, and continuous outcomes were assessed using the t test. Results: A total of 130 ACHD patients received the intervention, with no significant differences observed in clinical outcomes when compared with 89 controls. While there was additionally no reduction in hospital-related mortality (2.3% vs 7.8%, RR 0.3; P = .1), clinician ordering behaviors were better aligned with best-practices following the intervention. Among patients with moderate or greater anatomic complexity, a post hoc analysis demonstrated reduced in-hospital mortality from those who received the adult order set. Conclusions: The implementation of an adult-specific order set in a pediatric care setting did not improve clinical outcomes for all ACHD patients. Patients with moderate and greater anatomic complexity did see a mortality benefit, suggestive that targeted electronic tools may most benefit those who have the highest risk.
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Park et al. (2024) conducted a cohort in Adults with congenital heart disease (ACHD) post-cardiac surgery (n=219). Adult-specific order set vs. Control patients admitted prior to the intervention was evaluated on Hospital-related mortality (RR 0.3, p=.1). Implementation of an adult-specific order set in a pediatric ICU did not significantly reduce hospital-related mortality for all ACHD patients (2.3% vs 7.8%, RR 0.3; P=.1).
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