February 1, 1992Circulation
Electrogram criteria for identification of appropriate target sites for radiofrequency catheter ablation of accessory atrioventricular connections.
Key result
Radiofrequency ablation at sites with stable electrograms, accessory AV connection potentials, and specific timing features had a 57-82% success probability compared to 3-5% without these features.
Why the study?
Do specific local electrogram criteria predict the success of radiofrequency catheter ablation of accessory atrioventricular connections?
Population
132 patients undergoing radiofrequency catheter ablation of accessory atrioventricular connections with a…
Comparison
Radiofrequency catheter ablation at target sites… vs Radiofrequency catheter ablation at target sites…
Design
Cohort
Authors
Discussion
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Implication
Electrogram criteria may guide accessory pathway ablation site selection; supports refined mapping but leaves open prospective validation.
Study Design
Type
Observational (n=132)
Structured PICO
Do specific local electrogram criteria predict the success of radiofrequency catheter ablation of accessory atrioventricular connections?
P
Population
132 patients undergoing radiofrequency catheter ablation of accessory atrioventricular (AV) connections (90 manifest, 44 concealed) with a total of 438 ablation sites analyzed.
I
Intervention
Radiofrequency catheter ablation at target sites demonstrating specific local electrogram criteria (electrogram stability, presence of an accessory AV connection potential, and specific timing of ventricular activation or retrograde continuous electrical activity).
C
Comparator
Radiofrequency catheter ablation at target sites without these specific local electrogram features.
O
Outcome
Success or failure of radiofrequency catheter ablation at the target site.
Main Result
Absolute Event Rate: 57% vs 3%
p-value: p=<0.001
Specific local electrogram criteria, including electrogram stability and the presence of an accessory AV connection potential, strongly predict the procedural success of radiofrequency catheter ablation for accessory AV connections.
Cite This Study
Calkins et al. (1992) conducted an observational in Wolff-Parkinson-White syndrome or paroxysmal supraventricular tachycardia (n=132). Radiofrequency catheter ablation at sites with optimal electrogram features vs. Ablation at sites without optimal electrogram features was evaluated on Probability of ablation success at sites with optimal electrogram features (manifest connections) (p=<0.001). Radiofrequency ablation at sites with stable electrograms, accessory AV connection potentials, and specific timing features had a 57-82% success probability compared to 3-5% without these features.