Key result
Moderate patient-prosthesis mismatch after AVR shows no link to early mortality or postoperative events.
Why the study?
Patient-prosthesis mismatch is associated with adverse events, but its effect on early postoperative results after AVR in daily practice needed evaluation.
Does patient-prosthesis mismatch affect early postoperative outcomes in patients undergoing aortic valve replacement?
Observational (n=150)
No
Does patient-prosthesis mismatch affect early postoperative outcomes in patients undergoing aortic valve replacement?
Moderate patient-prosthesis mismatch after aortic valve replacement is relatively common but does not appear to adversely affect early postoperative mortality or complication rates.
Answers are grounded in this paper and cite their sources.
Moderate PPM after AVR may not affect early outcomes; leaves open its long-term prognostic relevance.
Introduction: Patient-prosthesis mismatch (PPM) has been associated with numerous short- and long-term adverse events. This study aimed to evaluate the effect of PPM on early postoperative results after aortic valve replacement (AVR) in daily practice. Methods: In this single-centre retrospective study, 150 non-consecutive patients from March 2019 to January 2020 with clinically indicated AVR with/without concomitant surgery were analysed. The study protocol included operative mortality, complication rate, and pre- and postoperative echocardiographic data. PPM was considered severe with indexed effective orifice area at <0.65 cm 2 /m 2 , moderate at 0.65–0.85 cm 2 /m 2 and none at >0.85 cm 2 /m 2 . Results: Moderate PPM was observed in 16 patients (10.6%). No patient had severe PPM. PPM was not related to early mortality ( r = 0.40, p = 0.630), intra- ( r = −0.076, p = 0.352) and postoperative ( r = −0.0134, p = 0.102) events. Conclusion: In this study, moderate PPM was a frequent finding after AVR, whereas severe PPM was not observed. PPM did not affect the early results after AVR. A long-term follow-up study in a large patient population is required to assess the actual influence of residual PPM.
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Aitaliyev et al. (2021) conducted an observational in Aortic valve replacement (n=150). Patient-prosthesis mismatch (PPM) vs. No PPM was evaluated on Early mortality (r = 0.40, p=0.630). Moderate patient-prosthesis mismatch occurred in 10.6% of patients undergoing aortic valve replacement but was not associated with early mortality (r=0.40, p=0.630) or postoperative events.
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