Key result
Epicardial, endocardial, and midmyocardial cells from the canine left ventricle display intrinsic differences in excitation-contraction coupling and calcium homeostasis to synchronize contraction.
Authors
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No immediate clinical implications; extends electrical heterogeneity observations to calcium homeostasis in canine myocytes.
Cordeiro et al. (2004) studied Basic electrophysiology and mechanics. Epicardial, endocardial, and midmyocardial cells was evaluated on Unloaded cell shortening, Ca(2+) transients, and inward L-type Ca(2+) current characteristics. Epicardial, endocardial, and midmyocardial cells from the canine left ventricle display intrinsic differences in excitation-contraction coupling and calcium homeostasis to synchronize contraction.
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