Why the study?
Is severe obesity associated with an increased risk of idiopathic dilated cardiomyopathy?
Is severe obesity associated with an increased risk of idiopathic dilated cardiomyopathy?
Severe obesity does not appear to be strongly associated with idiopathic dilated cardiomyopathy based on this pooled case-control analysis.
To learn more about the dilated form of cardiomyopathy associated with obesity, we conducted a pooled analysis of data from two case-control studies of idiopathic dilated cardiomyopathy. Up to two controls of the same sex and approximate age (+/- 5 years) had been selected for each case using random digit dialing. The subjects had been interviewed by telephone. We compared the cases (N = 224) and controls (N = 353) using conditional logistic regression. We defined severe obesity using national criteria for severely elevated body mass index. We found little association with severe obesity in multivariate analysis (relative odds = 1.1; 95% confidence interval = 0.7-1.9).
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Coughlin et al. (1996) studied this question.
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