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Clinical decision support systems (CDSS) are increasingly used by healthcare professionals for evidence-based diagnosis and treatment support. However, research has suggested that users often over-rely on system suggestions - even if the suggestions are wrong. Providing explanations could potentially mitigate misplaced trust in the system and over-reliance. In this paper, we explore how explanations are related to user trust and reliance, as well as what information users would find helpful to better understand the reliability of a system's decision-making. We investigated these questions through an exploratory user study in which healthcare professionals were observed using a CDSS prototype to diagnose hypothetic cases using fictional patients suffering from a balance-related disorder. Our results show that the amount of system confidence had only a slight effect on trust and reliance. More importantly, giving a fuller explanation of the facts used in making a diagnosis had a positive effect on trust but also led to over-reliance issues, whereas less detailed explanations made participants question the system's reliability and led to self-reliance problems. To help them in their assessment of the reliability of the system's decisions, study participants wanted better explanations to help them interpret the system's confidence, to verify that the disorder fit the suggestion, to better understand the reasoning chain of the decision model, and to make differential diagnoses. Our work is a first step toward improved CDSS design that better supports clinicians in making correct diagnoses.
Bussone et al. (Thu,) studied this question.