Key result
Exercise training in postmenopausal women with CAD increased VO2peak by 15% at 26 weeks (P<0.001), with consistent cardiovascular and peripheral adaptations regardless of HRT status.
Why the study?
Does hormone replacement therapy influence the central and peripheral cardiovascular effects of exercise training in postmenopausal women with CAD?
Cohort (n=38)
Does hormone replacement therapy influence the central and peripheral cardiovascular effects of exercise training in postmenopausal women with CAD?
p-value: p=<0.001
Exercise training improves cardiovascular responses in postmenopausal women with CAD, driven by peripheral adaptations, regardless of hormone replacement therapy status.
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Supports exercise benefits irrespective of HRT in postmenopausal CAD; hypothesis-generating and requires randomized confirmation.
Kirwan et al. (2003) conducted a cohort in Coronary Artery Disease (CAD) (n=38). Exercise training vs. Hormone replacement therapy (HRT) vs no HRT was evaluated on Peak oxygen uptake (VO2peak) (p=<0.001). Exercise training in postmenopausal women with CAD increased VO2peak by 15% at 26 weeks (P<0.001), with consistent cardiovascular and peripheral adaptations regardless of HRT status.
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