Why the study?
What are the hemodynamic determinants of survival in a canine model of cardiogenic shock?
Population
18 healthy mongrel dogs with induced myocardial infarction and cardiogenic shock
Design
Preclinical
Follow-up
up to 11 days
Authors
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May aid early detection of pump failure in cardiogenic shock models; leaves open clinical translation and outcome impact.
What are the hemodynamic determinants of survival in a canine model of cardiogenic shock?
Left ventricular dP/dt max is a key hemodynamic determinant for early diagnosis and prognosis of pump failure in cardiogenic shock.
Misra et al. (1970) studied this question.
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