Key result
New algorithm VT alerts linked to ~38% higher 30-day in-hospital mortality, unlike current bedside monitors.
Why the study?
Continuous ECG monitoring identifies ventricular tachycardia, but false alarms occur frequently in the ICU.
Do VT alerts from a new algorithm better predict 30-day in-hospital mortality compared to current bedside monitors in adult ICU patients?
Cohort (n=5,679)
No
Do VT alerts from a new algorithm better predict 30-day in-hospital mortality compared to current bedside monitors in adult ICU patients?
A new VT alert algorithm accurately identifies high-risk VT associated with 30-day in-hospital mortality, outperforming current bedside monitors which suffer from false alarms.
BackgroundContinuous electrocardiographic (ECG) monitoring is used to identify ventricular tachycardia (VT), but false alarms occur frequently.ObjectiveThe purpose of this study was to assess the rate of 30-day in-hospital mortality associated with VT alerts generated from bedside ECG monitors to those from a new algorithm among intensive care unit (ICU) patients.MethodsWe conducted a retrospective cohort study in consecutive adult ICU patients at an urban academic medical center and compared current bedside monitor VT alerts, VT alerts from a new-unannotated algorithm, and true-annotated VT. We used survival analysis to explore the association between VT alerts and mortality.ResultsWe included 5679 ICU admissions (mean age 58 ± 17 years; 48% women), 503 (8.9%) experienced 30-day in-hospital mortality. A total of 30.1% had at least 1 current bedside monitor VT alert, 14.3% had a new-unannotated algorithm VT alert, and 11.6% had true-annotated VT. Bedside monitor VT alert was not associated with increased rate of 30-day mortality (adjusted hazard ratio [aHR] 1.06; 95% confidence interval [CI] 0.88–1.27), but there was an association for VT alerts from our new-unannotated algorithm (aHR 1.38; 95% CI 1.12–1.69) and true-annotated VT(aHR 1.39; 95% CI 1.12–1.73).ConclusionUnannotated and annotated-true VT were associated with increased rate of 30-day in-hospital mortality, whereas current bedside monitor VT was not. Our new algorithm may accurately identify high-risk VT; however, prospective validation is needed. Continuous electrocardiographic (ECG) monitoring is used to identify ventricular tachycardia (VT), but false alarms occur frequently. The purpose of this study was to assess the rate of 30-day in-hospital mortality associated with VT alerts generated from bedside ECG monitors to those from a new algorithm among intensive care unit (ICU) patients. We conducted a retrospective cohort study in consecutive adult ICU patients at an urban academic medical center and compared current bedside monitor VT alerts, VT alerts from a new-unannotated algorithm, and true-annotated VT. We used survival analysis to explore the association between VT alerts and mortality. We included 5679 ICU admissions (mean age 58 ± 17 years; 48% women), 503 (8.9%) experienced 30-day in-hospital mortality. A total of 30.1% had at least 1 current bedside monitor VT alert, 14.3% had a new-unannotated algorithm VT alert, and 11.6% had true-annotated VT. Bedside monitor VT alert was not associated with increased rate of 30-day mortality (adjusted hazard ratio [aHR] 1.06; 95% confidence interval [CI] 0.88–1.27), but there was an association for VT alerts from our new-unannotated algorithm (aHR 1.38; 95% CI 1.12–1.69) and true-annotated VT(aHR 1.39; 95% CI 1.12–1.73). Unannotated and annotated-true VT were associated with increased rate of 30-day in-hospital mortality, whereas current bedside monitor VT was not. Our new algorithm may accurately identify high-risk VT; however, prospective validation is needed.
No takes yet. Share an insight, caveat, or question.
Prasad et al. (2023) conducted a cohort in adult ICU patients (n=5,679). VT alerts from a new-unannotated algorithm vs. current bedside monitor VT alerts was evaluated on 30-day in-hospital mortality (aHR 1.38, 95% CI 1.12-1.69). VT alerts from a new algorithm were associated with increased 30-day in-hospital mortality (aHR 1.38; 95% CI 1.12-1.69), whereas current bedside monitor VT alerts were not (aHR 1.06; 95% CI 0.88-1.27).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: