Why the study?
Does programmed electrical stimulation induce atrial flutter or fibrillation and reveal activation pathways in a canine model of left atrial enlargement?
Population
10 dogs with a shunt from the left subclavian artery to the left upper pulmonary vein created to produce…
Design
Preclinical
Follow-up
5 months
Authors
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Should not change practice; leaves open whether left atrial enlargement promotes similar reentry in human atrial arrhythmias.
Does programmed electrical stimulation induce atrial flutter or fibrillation and reveal activation pathways in a canine model of left atrial enlargement?
This canine model demonstrates that left atrial enlargement facilitates the induction of atrial flutter and fibrillation, with complex re-entrant pathways shaped by anatomical and functional barriers.
Yamauchi et al. (1998) studied this question.
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