Key result
The rate of NOAC initiation in the UK increased 17-fold from 2012 to 2015 (RR 17.68; 95% CI 12.16-25.71), surpassing VKAs to account for 56.5% of oral anticoagulant prescriptions in 2015.
Why the study?
What are the trends in the prescription of NOACs versus VKAs in UK primary care from 2009 to 2015?
Population
Patients in the UK primary care setting initiated on oral anticoagulants between 2009 and 2015
Comparison
Novel oral anticoagulants vs Vitamin-K antagonists (VKAs)
Design
Cohort
Authors
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NOAC uptake surged in UK primary care; observational trends leave open effects on long-term outcomes and adherence.
Observational
Yes
What are the trends in the prescription of NOACs versus VKAs in UK primary care from 2009 to 2015?
Effect estimate: RR 17.68 (95% CI 12.16, 25.71)
NOACs have rapidly been adopted in UK primary care, surpassing VKAs as the preferred oral anticoagulant by 2015.
Loo et al. (2017) conducted an observational in Thromboembolism prevention. Novel oral anticoagulants (NOACs) vs. Vitamin-K antagonists (VKAs) was evaluated on Rate of initiation of NOACs from 2012 to 2015 (RR 17.68, 95% CI 12.16, 25.71). The rate of NOAC initiation in the UK increased 17-fold from 2012 to 2015 (RR 17.68; 95% CI 12.16-25.71), surpassing VKAs to account for 56.5% of oral anticoagulant prescriptions in 2015.
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