Key result
Electric left atrial appendage isolation during catheter ablation was associated with an unexpectedly high incidence of LAA thrombus (21% vs 0%) and stroke compared to matched controls (P<0.001).
Why the study?
Does electric left atrial appendage isolation increase the risk of LAA thrombus formation and stroke in patients undergoing catheter ablation for atrial tachyarrhythmias?
Cohort (n=100)
Does electric left atrial appendage isolation increase the risk of LAA thrombus formation and stroke in patients undergoing catheter ablation for atrial tachyarrhythmias?
Absolute Event Rate: 21% vs 0%
p-value: p=<0.001
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Electrical isolation of the left atrial appendage during catheter ablation is associated with a significantly increased risk of LAA thrombus and stroke, even with oral anticoagulation.
Rillig et al. (2016) conducted a cohort in Atrial tachyarrhythmias (n=100). Electric left atrial appendage isolation (LAAI) vs. Atrial fibrillation ablation without LAAI was evaluated on LAA thrombus formation and thromboembolic events (p=<0.001). Electric left atrial appendage isolation during catheter ablation was associated with an unexpectedly high incidence of LAA thrombus (21% vs 0%) and stroke compared to matched controls (P<0.001).
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