Key result
Solutions to the inverse problem of electrocardiography accurately recovered epicardial potentials early during ventricular preexcitation, but not during the later QRS complex.
Why the study?
Does computational modeling using 3D finite element models and regularization accurately recover epicardial potentials from thoracic potentials in humans?
Case Report (n=1)
Does computational modeling using 3D finite element models and regularization accurately recover epicardial potentials from thoracic potentials in humans?
Computational recovery of epicardial potentials from thoracic leads is accurate during early ventricular preexcitation but struggles with more complex distributions later in the QRS complex.
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May inform early preexcitation mapping; leaves open accuracy for complex later QRS distributions.
Shahidi et al. (1994) conducted a case report in Arrhythmia (n=1). Inverse problem of electrocardiography solutions (Tykhonov regularization) vs. Directly measured epicardial potentials was evaluated on Accuracy of recovered epicardial potential distributions. Solutions to the inverse problem of electrocardiography accurately recovered epicardial potentials early during ventricular preexcitation, but not during the later QRS complex.
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