Key result
Myocardial segments with 76-100% hyperenhancement were 86 times less likely to show functional improvement after revascularization compared to segments without hyperenhancement (P<0.001).
Why the study?
Does the baseline extent of myocardial fibrosis predict the likelihood and time course of functional recovery after revascularization in patients with chronic ischaemic LV dysfunction?
Observational (n=35)
Does the baseline extent of myocardial fibrosis predict the likelihood and time course of functional recovery after revascularization in patients with chronic ischaemic LV dysfunction?
p-value: p=<0.001
In patients with chronic ischemic LV dysfunction, the likelihood and time course of functional recovery after revascularization are inversely related to the baseline extent of myocardial scar assessed by contrast-enhanced CMR.
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High scar on CMR predicts poor post-revascularization recovery; supports viability assessment but leaves open prospective outcome trials.
Бондаренко et al. (2008) conducted an observational in chronic ischaemic left ventricular (LV) dysfunction (n=35). Revascularization vs. Segments without hyperenhancement was evaluated on Functional improvement (p=<0.001). Myocardial segments with 76-100% hyperenhancement were 86 times less likely to show functional improvement after revascularization compared to segments without hyperenhancement (P<0.001).
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