Why the study?
What is the frequency and characteristics of ventricular late potentials detected by endocardiac mapping in patients with prior myocardial infarction?
What is the frequency and characteristics of ventricular late potentials detected by endocardiac mapping in patients with prior myocardial infarction?
Endocardiac mapping reveals that ventricular late potentials are common (71%) in patients with prior myocardial infarction and may correlate with delayed ventricular ectopic beats.
Late potentials common on endocardial mapping post-MI; hypothesis-generating for arrhythmia substrate, needs prospective validation before risk stratification use.
Left and right heart catheterization was conducted on 45 patients with a history of myocardial infarction in order to detect so-called ventricular late potentials by means of endocardiac mapping. The endocardiac signals were amplified 100 to 10,000 times at a low noise level using bipolar electrode catheters. The signals were stored unfiltered and visualized directly on an oscilloscope. Consistently recurring late potentials were recorded after QRS complexes in 32 patients (71%). They ranged in amplitude from 50 to 780 microV, while the coupling intervals were measured in the range of 80 to 620 ms from the beginning of the QRS complex to the beginning of the late potential. In some patients, the intracardially registered and/or Holter-monitored ventricular ectopic beats occurred with a delay, corresponding to the delayed occurrence of the ventricular late potentials.
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Bethge et al. (1984) studied this question.
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