Key result
Vagal ganglionated plexi ablation in addition to pulmonary vein isolation may be more effective than either approach alone for treating atrial fibrillation.
Why the study?
Does ablation or modification of vagal ganglionated plexi improve outcomes in patients with atrial fibrillation?
Does ablation or modification of vagal ganglionated plexi improve outcomes in patients with atrial fibrillation?
This review highlights the current data and discrepancies regarding the role and therapeutic implications of vagal ganglionated plexi ablation in atrial fibrillation.
Should not yet alter AF ablation practice; leaves open the need for RCTs amid data discrepancies.
Although pulmonary vein isolation is accepted as an established interventional treatment in paroxysmal atrial fibrillation (AF), alternative modalities are being investigated because of the high recurrence rates of nonparoxysmal forms. One of the alternative ablation approaches is ablation or modification of vagal ganglionated plexi (VGP). The technique has not only been used in vagally mediated AF but also investigated in paroxysmal and nonparoxysmal AF. Clinical studies demonstrate significant discrepancy related with detection of VGP sites or ablation targets and definition of procedurel end-points, so far. In this review, we aimed to discuss the current data on the role of VGP in the pathogenesis of AF and potential therapeutic implications of ablation of these ganglia.
No takes yet. Share an insight, caveat, or question.
Tolga Aksu (2017) conducted a review in Atrial fibrillation. Vagal ganglionated plexi (VGP) ablation vs. Pulmonary vein isolation (PVI) was evaluated. Vagal ganglionated plexi ablation in addition to pulmonary vein isolation may be more effective than either approach alone for treating atrial fibrillation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: