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August 1, 2009

The Autonomic Nervous System and Atrial Fibrillation:The Roles of Pulmonary Vein Isolation and Ganglionated Plexi Ablation.

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Why the study?

Does ganglionated plexi ablation combined with pulmonary vein isolation improve outcomes in patients with atrial fibrillation?

Population

Patients with atrial fibrillation (paroxysmal, persistent, and long-standing persistent)

Design

Review

Key result

Pulmonary vein isolation combined with ganglionated plexi ablation shows long-term success rates for atrial fibrillation comparable to myocardial ablation for other arrhythmias.

Authors

BSBenjamin J. ScherlagHNHiroshi NakagawaEPEugene Patterson

Discussion

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Overview

Supports adjunctive GP ablation in AF ablation; leaves open confirmation via randomized trials.

Structured PICO

Does ganglionated plexi ablation combined with pulmonary vein isolation improve outcomes in patients with atrial fibrillation?

P
Population
Patients with atrial fibrillation (paroxysmal, persistent, and long-standing persistent)
I
Intervention
Pulmonary vein isolation (PVI) and/or ganglionated plexi (GP) ablation

Ganglionated plexi ablation, either alone or combined with pulmonary vein isolation, may improve the success rates of atrial fibrillation ablation by targeting the intrinsic cardiac autonomic nervous system.

Cite This Study

Scherlag et al. (2009) conducted a review in Atrial Fibrillation. Pulmonary vein isolation and ganglionated plexi ablation was evaluated. Pulmonary vein isolation combined with ganglionated plexi ablation shows long-term success rates for atrial fibrillation comparable to myocardial ablation for other arrhythmias.

synapsesocial.com/papers/6a0e2b2bfeb2455d62c8339ahttps://doi.org/10.4022/jafib.177
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