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October 13, 2016Pacing and Clinical Electrophysiology

Impact of Anatomically Guided Ganglionated Plexus Ablation on Electrical Firing from Isolated Pulmonary Veins

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Why the study?

Does anatomically guided ganglionated plexus ablation terminate electrical firing from isolated pulmonary veins in patients with drug-refractory paroxysmal atrial fibrillation?

Population

12 patients with drug-refractory paroxysmal atrial fibrillation who exhibited persistent pulmonary vein…

Design

Case_series

Key result

Anatomically guided ganglionated plexus ablation terminated persistent pulmonary vein firing in 8 of 12 patients (66.7%) after initial pulmonary vein isolation.

Authors

RJRuhong JiangGHGEN‐SHENG HUQLQiang Liu

Discussion

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Member takes

Overview

Suggests GP ablation may suppress post-PVI PV firing; hypothesis-generating and requires prospective validation before clinical adoption.

Study Design

Type

Observational (n=12)

Structured PICO

Does anatomically guided ganglionated plexus ablation terminate electrical firing from isolated pulmonary veins in patients with drug-refractory paroxysmal atrial fibrillation?

P
Population
12 patients with drug-refractory paroxysmal atrial fibrillation who exhibited persistent pulmonary vein firing after successful pulmonary vein isolation and restoration of left atrial sinus rhythm (identified from a screening of 840 cases).
I
Intervention
Anatomically guided ganglionated plexus (GP) ablation adjacent to the pulmonary vein.
O
Outcome
Termination of pulmonary vein firing.surrogate

Anatomically guided ganglionated plexus ablation frequently terminates rapid electrical firing from isolated pulmonary veins, highlighting the role of autonomic interactions in atrial fibrillation mechanisms.

Cite This Study

Jiang et al. (2016) conducted an observational in Drug-refractory paroxysmal atrial fibrillation (n=12). Anatomically guided ganglionated plexus ablation was evaluated on Termination of pulmonary vein firing. Anatomically guided ganglionated plexus ablation terminated persistent pulmonary vein firing in 8 of 12 patients (66.7%) after initial pulmonary vein isolation.

synapsesocial.com/papers/6a0fbb4e2badbc352afe9eaahttps://doi.org/10.1111/pace.12957
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