Why the study?
Does ganglionated plexi ablation improve the maintenance of sinus rhythm in patients with symptomatic, drug-refractory, persistent atrial fibrillation?
Does ganglionated plexi ablation improve the maintenance of sinus rhythm in patients with symptomatic, drug-refractory, persistent atrial fibrillation?
Ganglionated plexi ablation alone has a modest success rate (38.2%) for maintaining sinus rhythm in longstanding persistent AF, but overall success increases to 59.6% when combined with repeat procedures including pulmonary vein isolation.
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GP ablation yields modest sinus rhythm maintenance in persistent AF; leaves open its adjunctive value pending randomized trials.
Pokushalov et al. (2010) studied this question.
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