Key result
Minimally invasive surgical pulmonary vein isolation with ganglionic plexi ablation achieved an overall single-procedure success rate of 46.6% at 60 months, with higher success in paroxysmal (51.8%) compared to persistent (28.2%) atrial fibrillation.
Why the study?
Does minimally invasive surgical pulmonary vein isolation, ganglionic plexi ablation, and left atrial appendage exclusion prevent recurrence of atrial arrhythmias in patients with symptomatic, drug-refractory lone atrial fibrillation?
Cohort (n=139)
No
Does minimally invasive surgical pulmonary vein isolation, ganglionic plexi ablation, and left atrial appendage exclusion prevent recurrence of atrial arrhythmias in patients with symptomatic, drug-refractory lone atrial fibrillation?
Minimally invasive surgical PVI with GP ablation and LAA exclusion provides moderate long-term freedom from atrial arrhythmias, with better outcomes observed in patients with shorter AF duration, smaller left atrial size, and no early recurrence.
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May inform selection for paroxysmal lone AF; leaves open comparative efficacy versus catheter ablation in randomized trials.
Zheng et al. (2013) conducted a cohort in Atrial Fibrillation (n=139). Minimally invasive surgical pulmonary vein isolation, ganglionic plexi ablation, and left atrial appendage exclusion was evaluated on Single-procedure success (freedom from atrial fibrillation, atrial flutter, or atrial tachycardia off antiarrhythmic drugs) at 60 months. Minimally invasive surgical pulmonary vein isolation with ganglionic plexi ablation achieved an overall single-procedure success rate of 46.6% at 60 months, with higher success in paroxysmal (51.8%) compared to persistent (28.2%) atrial fibrillation.
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