Key result
Minimally invasive surgical pulmonary vein isolation with ganglionic plexi ablation achieved an overall single-procedure success rate of 46.6% at 60 months in patients with atrial fibrillation.
Why the study?
Does minimally invasive surgical PVI combined with GP ablation and LAA exclusion prevent arrhythmia recurrence in patients with symptomatic drug-refractory lone AF?
Cohort (n=139)
No
Does minimally invasive surgical PVI combined with GP ablation and LAA exclusion prevent arrhythmia recurrence in patients with symptomatic drug-refractory lone AF?
Minimally invasive surgical PVI with GP ablation and LAA exclusion provides moderate long-term freedom from atrial arrhythmias, with better outcomes observed in patients with shorter AF duration and smaller left atrial size.
Moderate long-term success cautions against routine adoption; leaves open need for RCTs versus catheter ablation in lone AF.
Background: Ganglionated plexi (GP) ablation has been become an adjunct to pulmonary vein isolation (PVI). This study describes the long-term results of minimally invasive surgical PVI, ablation of GPs, and exclusion of the left atrial appendage for atrial fibrillation (AF).
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Zheng et al. (2014) conducted a cohort in Atrial Fibrillation (n=139). Minimally invasive surgical pulmonary vein isolation and ganglionic plexi ablation was evaluated on Freedom from atrial fibrillation, atrial flutter, or atrial tachycardia off antiarrhythmic drugs at 60 months. Minimally invasive surgical pulmonary vein isolation with ganglionic plexi ablation achieved an overall single-procedure success rate of 46.6% at 60 months in patients with atrial fibrillation.
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