Why the study?
Does achieving a vagal response during pulmonary vein isolation and ablation of cardiac autonomic nerves reduce atrial fibrillation recurrence in patients with atrial fibrillation?
Population
21 patients with paroxysmal atrial fibrillation (n = 17) or persistent atrial fibrillation (n = 4).
Comparison
Radiofrequency ablation of each pulmonary vein… vs Patients who did not develop a vagal response…
Design
Cohort
Authors
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Vagal response during PVI was associated with lower AF recurrence; leaves open whether intentional targeting improves outcomes.
Does achieving a vagal response during pulmonary vein isolation and ablation of cardiac autonomic nerves reduce atrial fibrillation recurrence in patients with atrial fibrillation?
Achieving a vagal response during radiofrequency ablation for pulmonary vein isolation is associated with a decreased rate of atrial fibrillation recurrence.
Ohkubo et al. (2008) studied this question.