Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 1, 1991Proceedings of the National Academy of SciencesOpen Access

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

View Full Paper
Ask AI
Bookmark
Share

Authors

JCJohn M. CarneyDuke Medical CenterPSPamela Starke‐ReedAgricultural Research ServiceCOConstance OliverMerck & Co., Inc., Rahway, NJ, USA (United States)

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Carney et al. (1991) studied this question.

synapsesocial.com/papers/6a1566255347fbb1739fb92dhttps://doi.org/10.1073/pnas.88.9.3633
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain.1990 · 777 citations
  2. 2Regulation of glutamine synthetase in cultured 3T3-L1 cells by insulin, hydrocortisone, and dibutyryl cyclic AMP1978 · 120 citations
  3. 3The aging process.1981 · 1,921 citations
  4. 4Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing1983 · 468 citations