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The rhizosphere, phyllosphere and endosphere of plants are a collection of microorganisms simply called as the plant microbiome, essential to the health and protection of plants. Responses of plants to soil-borne diseases, which cause large-scale agricultural losses worldwide, are significantly impacted by this microbiome. According to recent study, there is a chance to confront these infections by using plant-associated microbiomes as an environmentally beneficial substitute for current chemical control methods. Examining the state of plant microbiome research in relation to managing soil-borne pathogens, this review highlights important discoveries and developments. It investigates the processes such as resource competition, antimicrobial synthesis, and stimulation of plant defense responses by which advantageous microorganisms give plants resistance. Notwithstanding encouraging outcomes, a number of obstacles stand in the way of using microbiome-based treatments in practical applications. These include the complicated nature of the relationships between microbes, the variation in the structure of the microbiome in various soils and environments, and the requirement for scalable and reliable application techniques. In order to overcome these obstacles, future studies must improve our knowledge of the dynamics of microbial communities, make use of cutting-edge genomic and metagenomic technologies, and combine sustainable farming methods with microbiome management techniques. This all encompassing strategy could transform disease control and improve food security worldwide. 1. The function of the plant microbiome is to optimize nutrient uptake, control diseases, and promote plant health. 2. Environmental factors, crop species, and soil type all determine the plant microbiome, which determines production and disease resistance. 3. Excessive use of fungicides damages soil health, encourages disease resistance, and reduces microbial diversity. 4. It's still difficult to guarantee microbial stability and efficacy in a variety of natural environments. Widespread use is restricted by high production costs and scaling problems. 5. For optimal microbiome-based solutions, developments in artificial intelligence, synthetic biology, and policy support are required.
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Chandrasekaran et al. (2025) studied this question.
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