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Critical evaluation of clinical trials is essential prior to applying results into clinical practice. We have created the acronym, PIES (Population, Intervention, Endpoints, and Statistics) that encapsulates the four basic aspects of a trial. The PIES method creates a systematic approach to critically evaluating a trial, allowing practitioners to formulate opinions as to the applicability to clinical practice.
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Baroletti et al. (2004) studied this question.
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