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December 19, 1996New England Journal of Medicine

Mechanisms of Muscle Wasting — The Role of the Ubiquitin–Proteasome Pathway

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Authors

WMWilliam E. MitchBaylor College of MedicineAlfred L. GoldbergAlfred L. GoldbergHarvard University

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Cite This Study

Mitch et al. (1996) studied this question.

synapsesocial.com/papers/6a15697e37103a43379fb38ehttps://doi.org/10.1056/nejm199612193352507
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription.1996 · 352 citations
  2. 2Whole Body Protein Kinetics in Severely Septic Patients1987 · 278 citations
  3. 3Interleukin-6 Induces Skeletal Muscle Protein Breakdown in Rats1994 · 296 citations
  4. 4Aggressive Nutritional Support Does Not Prevent Protein Loss Despite Fat Gain in Septic Intensive Care Patients1987 · 477 citations
  5. 5Suppression of muscle protein turnover and amino acid degradation by dietary protein deficiency1992 · 59 citations