Key result
COPD in patients with acute coronary syndrome was associated with increased heart failure (P=0.001) and bleeding complications (2.8% vs 1%, P=0.04), but not in-hospital mortality.
Why the study?
Does the presence of COPD worsen in-hospital outcomes in patients with acute coronary syndrome?
Population
8167 consecutive patients hospitalized with acute coronary syndrome (ACS) in 6 Middle Eastern countries
Comparison
Presence of clinically recognized chronic… vs Absence of COPD
Design
Cohort
Follow-up
in-hospital
Authors
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Warrants monitoring for HF and bleeding in ACS with COPD; hypothesis-generating, needs prospective validation before practice change.
Cohort (n=8,167)
Yes
Does the presence of COPD worsen in-hospital outcomes in patients with acute coronary syndrome?
In Middle Eastern patients with ACS, COPD is associated with atypical presentations, less use of evidence-based therapies, and higher rates of heart failure and bleeding, though in-hospital mortality is not significantly increased.
Hadi et al. (2010) conducted a cohort in Acute Coronary Syndrome (n=8,167). Chronic Obstructive Pulmonary Disease (COPD) vs. No COPD was evaluated on In-hospital outcomes (mortality, heart failure, and bleeding complications). COPD in patients with acute coronary syndrome was associated with increased heart failure (P=0.001) and bleeding complications (2.8% vs 1%, P=0.04), but not in-hospital mortality.
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