Key result
Endocardial microwave ablation using a new box lesion line concept significantly increased the rate of stable sinus rhythm at 1 year compared to a single lesion line concept (74% vs. 52%; P=0.0026).
Why the study?
Does a box lesion line concept improve sinus rhythm conversion compared to a single lesion line concept in patients undergoing intraoperative endocardial microwave ablation for permanent atrial fibrillation during cardiac surgery?
Population
102 consecutive patients with permanent atrial fibrillation undergoing coronary artery bypass surgery alone…
Comparison
Intraoperative endocardial microwave ablation… vs Intraoperative endocardial microwave ablation…
Design
Cohort
Follow-up
1 year
Authors
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Box lesion concept may raise sinus rhythm rates in surgical microwave ablation; extends simplified ablation strategies but remains hypothesis-generating pending RCTs.
Cohort (n=102)
Does a box lesion line concept improve sinus rhythm conversion compared to a single lesion line concept in patients undergoing intraoperative endocardial microwave ablation for permanent atrial fibrillation during cardiac surgery?
Absolute Event Rate: 74% vs 52%
p-value: p=0.0026
Intraoperative endocardial microwave ablation using a box lesion line concept during CABG or valve surgery significantly improves the rate of stable sinus rhythm at 1 year compared to a single lesion line concept.
Knaut et al. (2005) conducted a cohort in permanent atrial fibrillation (n=102). endocardial microwave ablation (box lesion line concept) vs. endocardial microwave ablation (single lesion line concept) was evaluated on stable sinus rhythm at 1-year follow-up (p=0.0026). Endocardial microwave ablation using a new box lesion line concept significantly increased the rate of stable sinus rhythm at 1 year compared to a single lesion line concept (74% vs. 52%; P=0.0026).
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