Why the study?
What is the mechanism initiating ventricular fibrillation in cultured rat embryo ventricular muscle tissue exposed to aconitine or strophanthin?
Population
Cultured ventricular muscle strips of the rat embryo heart
Design
Preclinical
Authors
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Does not support changes in clinical VF management; leaves open single-focus mechanisms beyond this embryo model.
What is the mechanism initiating ventricular fibrillation in cultured rat embryo ventricular muscle tissue exposed to aconitine or strophanthin?
This preclinical study demonstrates that fibrillation-like arrhythmias induced by aconitine or strophanthin in cultured rat embryo ventricular muscle originate from a single focus.
Sano et al. (1970) studied this question.
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