Key result
Endothelial dysfunction serves as a precursor to atherosclerosis and a predictor of future cardiovascular events, though currently there are no FDA-approved treatments specifically for it.
This review highlights the pathophysiological role of endothelial dysfunction in cardiovascular disease and outlines current modalities for its clinical and research assessment.
Absence of approved treatments for endothelial dysfunction warrants clinical caution; leaves open targeted therapy development and assessment standardization.
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Widmer et al. (2014) conducted a review in Endothelial dysfunction and cardiovascular disease. Endothelial dysfunction serves as a precursor to atherosclerosis and a predictor of future cardiovascular events, though currently there are no FDA-approved treatments specifically for it.
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